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Sheep Placenta and Depression

Sheep placenta is an organ formed in the uterus of the pregnant animal. The organ is vital for nourishment and support of the foetus. Sheep placenta is well-known for its incredible nutritional content which explains why supplements with this extract are highly sought after. The placenta of the sheep is a great source of estrogen, progesterone, peptides, antioxidants, hyaluronic acid, and many other nutrients and bioactive compounds that support a user’s health and wellbeing. While sheep placenta is primarily known for its rejuvenating effects, it does more than that. For example, supplementation with sheep placenta can help you manage depression, too.

How does NutriNZ Sheep Placenta help manage Depression?

Depression is more than a feeling of sadness and despair; it is a mental health condition that exhibits a number of both physical and emotional symptoms. Sudden weight gain or weight loss due to appetite changes, memory problems, impaired sleep patterns, are just some of many consequences associated with depression. Many risk factors are linked with the onset of depression and hormonal imbalance is one of them. This is where sheep placenta steps in.

NutriNZ Sheep placenta is a rich source of CRH (Corticotropin-releasing hormone), a hormone produced by the hypothalamus. CRH is chemically categorized as a neuropeptide hormone and its primary role is to act as a central driver of the stress hormone system, known as hypothalamic-pituitary-adrenal axis.

It is a little-known fact that CRH circuits tend to be overactive among patients with depression and this phenomenon is reflected by enhanced levels of cortisol and corticotrophin in the peripheral blood of the patients. Receptors associated with this hormone are responsible for conveying CRH signal into cellular circuitries. The result of this action is the onset of depressive symptoms[1]. A growing body of evidence confirms that depression is correlated with hypersecretion of the CRH. The excessive secretion of the hormone leads to behavioural symptoms of depression involving sleep and appetite disturbances, low libido, and psychomotor changes[2].

Therefore, normalizing levels of this important hormone plays a big role in depression management, thus helping patients improve their quality of life.

Estrogen Balance

Besides CRH whose impact on the development of depression is well-documented, it is also important to mention estrogen, yet another hormone present in sheep placenta. This hormone is vital for every woman’s wellbeing and both physical and emotional health.

After all, women are more prone to depression than men and a higher risk of developing this mood disorder has a lot to do with estrogen. Declining levels of this essential hormone are strongly implicated in the regulation of behaviour and mood as well as in the pathobiology of other disorders. Estrogen exhibits anti-depressive effects on receptors and neurotransmitters in your brain. When the levels of this hormone start to decline, these effects diminish and a woman becomes more likely to develop depression or some other mood disorder.

Estrogen receptors are the most prevalent in amygdala which responds to the hormone in a multifaceted manner that is exhibited through mood regulation. Moreover, this hormone exerts beneficial actions on the hippocampus which are directly related to mood symptomology. Estrogen depletion can lead to hippocampal changes that open the door for mood problems with depression and anxiety being the most common[3].

The concentration of this hormone is not consistent throughout your life, it fluctuates. In order to reduce the risk of problems that occur due to depleting estrogen, it is important to support hormonal balance in a natural way and sheep placenta can help you with that.

Sheep Placenta from NutriNZ

NutriNZ’s Sheep Placenta comes with Grapeseed Extract and Vitamin-E  to deliver antioxidants, peptides, hyaluronic acid, and many other substances including much-needed hormones. The result of regular intake is better mood and successful depression management through hormonal balance. 

Supporting Products

References

[1] Holsboer F. Corticotropin-releasing hormone modulators and depression. Current Opinion in Investigational Drugs 2003 Jan;4(1):46-50 https://www.ncbi.nlm.nih.gov/pubmed/12625028

[2] Arborelius L, Owens MJ, Plotsky PM, Nemeroff CB. The role of corticotrophin-releasing factor in depression and anxiety disorders. Journal of Endocrinology 1999 Jan;160(1):1-12 https://www.ncbi.nlm.nih.gov/pubmed/9854171

[3] Wharton W, Gleason CE, Olson SRMS, Carlsson CM, Asthana S. Neurobiological Underpinnings of the Estrogen – Mood Relationship. Current psychiatry reviews. 2012;8(3):247-256. doi:10.2174/157340012800792957. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753111/